Cancer remains one of humanity's most complex challenges. For generations, physicians have made treatment decisions based largely on what they could see under a microscope, where a tumor originated and how similar patients responded in the past. Today, that paradigm is changing. We are entering an era where cancer can be understood at the molecular level, revealing the … [More]
Translating Scientific Discoveries into Viable Diagnostics
As one of Castle Biosciences’ three original founders, I have had the privilege of helping the company grow from a small, early-stage organization into a leading diagnostics company serving patients and clinicians across the country. Castle began operations in 2008 and established its first laboratory presence in Phoenix the same year. From the beginning, our goal has been to … [More]
Manufacturing Biosensing Technology at Scale
At Dexcom, we make glucose biosensing technology that gives people living with and without diabetes real-time visibility into their glucose levels. For millions of people, biosensing technology transforms diabetes management and daily life by putting actionable data directly into the hands of users and their care teams. The shift from reactive treatment to proactive management … [More]
Furthering Breakthroughs in Regenerative Medicine
Humabiologics is a Phoenix-based regenerative medicine company making human biomaterials more accessible to scientists, clinicians and product developers in regenerative medicine, tissue engineering, bioprinting, organoids, disease modeling and drug discovery. Our mission is to give researchers more human-relevant building blocks to develop better therapies and more predictive … [More]
Translating Innovation into Impact for Ultra-Rare (and Commercially Underserved) Diseases
When people ask me what has fueled the rapid growth of Greater Phoenix's bioscience sector, I don't start by talking about funding or facilities. I talk about collaboration. Throughout my career, I've had the opportunity to work across clinical research, healthcare innovation, venture investing and biotechnology. I've seen what happens when researchers, physicians, … [More]
Advancing Non-Invasive Pain Management against One of Healthcare’s Most Persistent Challenges
Regenesis was founded with a simple but meaningful mission: to improve quality of life by developing innovative medical technologies that help relieve pain. Today, we continue that mission by researching, designing, manufacturing and supporting energy-based medical devices that expand access to safe, non-invasive, drug-free pain management solutions for patients and … [More]
Ensuring Domestic Sourcing for Medicine Essentials
Bright Path manufactures essential medicines — the generic, small-molecule drugs that hospitals, clinics and pharmacies depend on every day — in Mesa, at our facility at Falcon Field. Most Americans don't realize that the active pharmaceutical ingredients in the majority of these medicines are made overseas, which is why drug shortages have become a recurring crisis for … [More]
Skilled Trades, Big Opportunity in the Construction Boom
How Arizona business leaders can help close the workforce gap
Arizona is in the middle of the largest construction boom in its history, and the trades workforce needed to sustain it is shrinking. TSMC's $165-billion semiconductor campus in North Phoenix alone is expected to generate more than 40,000 construction jobs over four years. Add the surge of data centers and industrial expansion across the Valley, and the challenge becomes clear: … [More]
Where Hospitality Meets Housing: The Rise of Resort-Adjacent Residential Communities in Phoenix
In Phoenix, where rapid growth continues to reshape both skyline and lifestyle, a shift is underway in how multifamily housing is conceived. Increasingly, the line between where people live and how they experience that environment is blurring as developers blend residential design with elements once reserved for hotels and resorts. Across high-growth markets, resort-adjacent … [More]
The Ripple Effect of Semiconductor Partnerships in Arizona
Arizona’s semiconductor expansion is beginning to reach beyond fabs and factory floors, creating ripple effects across workforce training, university research, business development and the state’s broader innovation economy. Partnerships between companies such as Taiwan Semiconductor Manufacturing Co. and Amkor Technology are one example of how major industry investments can … [More]
McKinsey Study Puts New Numbers on U.S. Chip Workforce Challenge
The jobs are there – or are coming – but where’s the career interest?
The conversation around the semiconductor workforce can sound like a glass-half-empty story. The numbers are big, the gaps are real and the timeline is tight. But the same numbers point to one of the clearest career opportunities for students being told the job market is harder to break into. The New York Fed reported that labor market conditions remained challenging for … [More]
Why Arizona Is Ground Zero for Rethinking Primary Care Access
Arizona is not an easy place to deliver healthcare. That is precisely why it has become the proving ground for a different model of primary care. The structural realities are stark. Arizona faces a shortage of more than 4,000 physicians and 4,600 nurses, and today only about 35% of primary care needs are being met, according to Arizona Business Leadership. In some parts of … [More]
9 Efficiency Hacks Every Entrepreneur Should Implement Today
Phoenix ranks seventh nationally in the number of startups. But, with so many entrepreneurs getting their businesses off the ground, there is immense competition and pressure to move fast without wasting time or capital. These nine efficiency tips are designed to help startups save time, control costs and build scalable processes that support sustainable growth — both now and … [More]
Mark Davis: Brewing Black Rock Coffee Bar’s Next Chapter
And protecting the people-first culture that rang the Nasdaq bell
When I took over as CEO of Black Rock Coffee Bar in the spring of 2023, I inherited a company with something most leaders only dream of: a culture so strong that guests could feel it the moment they walked in the door. Baristas knew regulars by name and drink, asked first-timers about their day before steering them toward a flavor, and treated the counter like the start of a … [More]
Overall Giving Surpasses $600 Million
Giving USA 2025 report highlights widespread generosity
Even amid a year rife with governmental policy change — taxation, funding, environmental, healthcare, social justice — American philanthropists rallied. In fact, they showed just how quickly money can be mobilized in the face of challenge. Of any natural disaster worldwide, California’s 2025 wildfires generated the largest amount of donations — $860–970 million — in the … [More]
Hospitality Is a Verb: Designing Experiences People Remember
The design industry has spent years talking about experience. Hotels, restaurants, workplaces and mixed-use developments all aspire to create memorable moments that keep people coming back. But there is a challenge: Memorable experiences cannot be manufactured. Amenities can be replicated and beautiful interiors can be copied. What separates one place from another is … [More]
Why Middle-Market Companies Need Bankers Who Look beyond the Balance Sheet
Challenges in Metro Phoenix’s rapidly changing business landscape
As the leading metro for business activity in Arizona, Phoenix is evolving rapidly. What began as a metro focused predominantly on real estate and construction has expanded to a robust technology, manufacturing and life sciences hub. With a changing business landscape comes the need for new solutions, opportunities and partnerships. The State of Arizona provides relocation … [More]
Remote Work Did Not Fail Young Workers – Management Did
Flexibility and development are not mutually exclusive
For months, artificial intelligence was cast as the villain behind rising youth unemployment. AI was supposedly eliminating entry-level jobs, replacing junior workers and making it harder for recent graduates to get their foot in the door. Then the Federal Reserve Bank of New York introduced a different explanation. According to a recent analysis, remote work, not AI, may … [More]
